An Uncommon Dermatologic Emergency Caused by a Commonly prescribed Drug

The skin is considered the largest organ in the human body [1]. Consist of three principal layers; the epidermis, dermis and the hypodermis. Many functions are attributed, it served as our first and biggest barrier that protect us from microorganism, helps regulate body temperature, and permits the sensations of touch, heat, and cold. It is also responsible of nutrient absorption, among others [1]. The most common pathologies affecting skin are acne, infections, traumas and rash1. However life threatening condition such as Toxic epidermal necrolys is uncommon [1]. Toxic Epidermal Necrolysis (TEN) and Stevens Johnson syndrome (SJS) are severe skin reactions, most commonly triggered by drugs [2]. TEN involves greater than 30% of skin detachment [2]. Mortality may be as high as 40 to 50% [3]. Estimates of incidence range from two to seven cases per million people per year, with no age predominance.